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EpiPen Auto injector/ml im

EpiPen Auto injector/ml im

Active Ingredient: Adrenaline (epinephrine)

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Medical Information

About This Medicine

EpiPen is a pre-filled auto-injector delivering adrenaline (epinephrine) for the emergency treatment of severe allergic reactions (anaphylaxis). Anaphylaxis can be triggered by foods, insect stings, medications, or latex and can be life-threatening if not treated promptly. Adrenaline reverses the effects of anaphylaxis by constricting blood vessels, relaxing the airways, and supporting cardiac output. The auto-injector design allows patients and carers to administer the drug quickly without medical training.

Usage & Dosage

How to Use an EpiPen

Remove the EpiPen from its carrier tube. Pull off the blue safety cap. Hold the orange tip pointing downward and press the orange tip firmly against the outer mid-thigh (you can inject through clothing if necessary). Press firmly and hold in place for 10 seconds after you hear the click. Remove the EpiPen and massage the injection site for 10 seconds. The window will darken when the injection is complete.

Call emergency services (999 or 112) immediately after use — adrenaline is a temporary measure and medical assessment is always required after anaphylaxis, even if symptoms improve. A second EpiPen may be used after 5 to 15 minutes if symptoms return or do not fully resolve.

After Use

Always seek emergency medical care even if you feel better after the injection. Symptoms of anaphylaxis can return (biphasic reaction) several hours later. Always carry two EpiPens at all times if prescribed.

EpiPen (adult): 300 mcg adrenaline per injection. EpiPen Junior (children 15 to 30 kg): 150 mcg. A second injection may be given after 5 to 15 minutes if symptoms do not improve. Always carry two auto-injectors.

Side Effects

Expected Effects After Injection

The following effects are normal responses to adrenaline and confirm the medicine is working:

  • Rapid or strong heartbeat (palpitations)
  • Tremor or shakiness
  • Anxiety or a sense of urgency
  • Pallor (pale skin)
  • Headache
  • Dizziness

Reassurance

These sensations are temporary and are the expected result of adrenaline releasing into the bloodstream. They generally settle within 15 to 30 minutes. If you have heart disease or are taking certain medicines (such as beta-blockers), the response may be different — discuss emergency planning with your doctor or allergy specialist. An EpiPen should never be withheld during a suspected anaphylactic reaction out of concern about these side effects.

Warnings & Precautions

Always call emergency services after using an EpiPen, even if symptoms improve, as anaphylaxis can recur (biphasic reaction). Check the expiry date regularly. Store at room temperature; do not refrigerate. Replace if the solution appears discoloured or contains particles.

Contraindications

There are no absolute contraindications in the setting of life-threatening anaphylaxis. Adrenaline is the only first-line treatment for anaphylaxis and should always be administered when anaphylaxis is suspected.

Frequently Asked Questions

Can I use an expired EpiPen in an emergency?
If no in-date EpiPen is available during anaphylaxis, an expired pen should still be used, as some adrenaline activity is retained for months after expiry. However, always aim to replace expired pens promptly and still call emergency services after use.
Medically Reviewed

Dr. Ross Elledge

General Practitioner · General & Family Medicine

Verified Healthcare Professional

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