EU Licensed
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Imigran Nasal spray 6 doses

Imigran Nasal spray 6 doses

Active Ingredient: Sumatriptan succinate

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Medical Information

About This Medicine

Imigran is the original branded sumatriptan, the first triptan developed for acute migraine treatment. It is available as tablets, nasal spray, and subcutaneous injection. The injection provides the fastest onset (within 10 minutes) and is used for severe attacks or when vomiting prevents oral or nasal administration. Sumatriptan constricts dilated cranial blood vessels and inhibits inflammatory neuropeptide release.

Usage & Dosage

How to Take Imigran

Take Imigran (sumatriptan) as soon as the migraine headache begins. It is not intended for prevention and does not work if taken before the headache phase starts. Tablets should be swallowed whole with water. For the nasal spray, administer one spray into one nostril. For the injection, inject subcutaneously into the outer thigh or upper arm.

If the migraine returns after initial relief, a second dose may be taken at least two hours after the first. Do not take more than two doses in 24 hours. If the first dose provides no relief at all during the same attack, a second dose is unlikely to help and should not be taken for that attack.

Tablets: 50 to 100 mg per dose, maximum 300 mg daily. Nasal spray: 10 to 20 mg, maximum 40 mg daily. Injection: 6 mg subcutaneously, maximum 12 mg daily.

Side Effects

Common Side Effects

Common side effects include:

  • Tingling, warmth, or flushing
  • Chest tightness or pressure (usually brief and benign, but see below)
  • Heaviness or pressure in the limbs
  • Drowsiness
  • Nausea
  • Injection site reactions (with the injection form)

Chest tightness is reported by some people taking Imigran and is usually a transient, non-cardiac effect. However, if chest pain is severe, lasts more than a few minutes, or radiates to the arm or jaw, seek emergency medical care immediately, as triptans should not be used in patients with heart disease.

Warnings & Precautions

Not for hemiplegic or basilar migraine. Do not use within 24 hours of another triptan or ergotamine. Cardiovascular assessment recommended before first use in patients with risk factors.

Contraindications

Contraindicated in ischaemic heart disease, uncontrolled hypertension, previous stroke or TIA, severe hepatic impairment, and concurrent MAO inhibitor use.

Frequently Asked Questions

Is Imigran available without a prescription?
In the UK, sumatriptan 50 mg tablets are available over the counter from pharmacies (sold as Imigran Recovery). The pharmacist will ask a few questions to ensure it is suitable. Higher doses and other formulations require a prescription.
Medically Reviewed

Dr. Ross Elledge

General Practitioner · General & Family Medicine

Verified Healthcare Professional

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