Priligy

Priligy contains dapoxetine, the only oral medication specifically licensed in Europe for the on-demand treatment of premature ejaculation (PE) in adult men aged 18 to 64. Dapoxetine belongs to the selective serotonin reuptake inhibitor (SSRI) class but, unlike SSRIs used for depression, it has been designed for rapid absorption and short duration of action, making it suitable for use before sexual activity rather than as a daily medication.

Premature ejaculation is one of the most common male sexual health concerns, and dapoxetine addresses it by increasing serotonin activity in the nervous system. Higher serotonin levels raise the ejaculatory threshold, helping men to delay ejaculation and experience greater control during intercourse.

How to Take Priligy

Take one tablet with a full glass of water, one to three hours before anticipated sexual activity. Priligy can be taken with or without food, though taking it on an empty stomach may speed up absorption. Do not take more than one dose within any 24-hour period.

Avoid standing up quickly after taking Priligy, particularly during the first few doses, as it may cause dizziness or lightheadedness. If you feel faint, sit or lie down until the sensation passes. Stay well hydrated before and after taking the medication.

The starting dose is 30 mg. If 30 mg is well tolerated but does not provide sufficient improvement in ejaculatory control, the dose may be increased to 60 mg on subsequent occasions. Your prescriber will review your response and tolerability after the first four weeks of treatment before recommending a dose adjustment.

Common Side Effects

The most commonly reported side effects include:

• Nausea
• Dizziness
• Headache
• Diarrhoea

Dizziness and fainting (syncope) can occur, particularly when standing up too quickly or in combination with alcohol. If you experience pre-fainting symptoms such as lightheadedness, sweating, or nausea, lie down immediately with your legs raised. These effects are generally mild and become less frequent with continued use.

Priligy is not suitable for men with heart conditions including heart failure, conduction abnormalities (such as heart block), or significant valvular disease. It should not be used by men with a history of syncope (fainting), mania, severe depression, or moderate to severe liver impairment.

Do not combine dapoxetine with MAO inhibitors, other SSRIs or SNRIs, thioridazine, or serotonergic herbal supplements such as St John's Wort. These combinations increase the risk of serotonin syndrome, a potentially dangerous condition. Alcohol significantly increases the risk of dizziness and fainting when taken with Priligy and should be avoided.

Priligy is contraindicated in patients with heart failure, conduction abnormalities, ischaemic heart disease, significant valvular disease, or a history of syncope. It must not be used by men with severe hepatic impairment or those concurrently taking SSRIs, SNRIs, MAO inhibitors, or thioridazine. It is not approved for use in men under 18 or over 64.